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KMID : 0359819950240050497
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Journal of Korean Neurosurgical Society
1995 Volume.24 No. 5 p.497 ~ p.504
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Development of Experimental 0L Glosarcoma Rat Brain Tumor Model
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김종현
이승훈/이창훈/윤상민
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Abstract
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Experimental brain tumor model is essential for the development of new therapeutic modalities of brain tumors and evaluation of efficacy of each therapeutic variety. Authors developed experimental rat brain tumor model with 9L and C6 cell line in
Fischer rat using stereotactic method. We tried to determine the tumor occurrence rare. the ideal time for secondary experiment using this brain tumor model. and the duration between the onset of neurological signs and the time of expiration. We
performed autoradiography for each cell line to evaluate the reliance of the tumor model. We could make good tumor model in all the cases of experiment and expect to use it in another extension of experiment.
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KEYWORD
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